DERIVATIZED TRIS-CATECHOL CHELATING AGENTS

Bifunctional chelating agents are designed to sequester certain radioactive metals, such as gallium (III) isotopes, and to provide a means for covalently attaching these radionuclides to macromolecules, such as monoclonal antibodies. These chelating agents may be used in various therapeutic and diag...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GANSOW, OTTO, A, MCMURRY, TOM
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Bifunctional chelating agents are designed to sequester certain radioactive metals, such as gallium (III) isotopes, and to provide a means for covalently attaching these radionuclides to macromolecules, such as monoclonal antibodies. These chelating agents may be used in various therapeutic and diagnostic methods, such as in radioimaging and positron emission tomography. L'invention se rapporte à des agents de chélation bifonctionnels qui sont conçus pour séquestrer certains métaux radioactifs, tels que les isotopes du gallium (III), et qui constituent un moyen permettant de fixer par covalence ces radionucléides à des macromolécules, tels que des anticorps monoclonaux. Ces agents de chélation peuvent être utilisés dans diverses techniques thérapeutiques et diagnostiques, telles que l'imagerie radio-immunologique et la tomographie par émission de positons.