ANTIHYPERTENSIVE COMPOSITIONS AND USE THEREOF

This invention concerns antihypertensive compositions and a method of lowering blood pressure in mammals. The active component of the composition is a compound of formula (I), wherein J is an organic or inorganic moiety, M?+x is a pharmaceutically acceptable cation and the compound decomposes under...

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Bibliographische Detailangaben
Hauptverfasser:	DUNAMS, TAMBRA, MARIE, HRABIE, JOSEPH, ANTHONY, WINK, DAVID, ANDERSON
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention concerns antihypertensive compositions and a method of lowering blood pressure in mammals. The active component of the composition is a compound of formula (I), wherein J is an organic or inorganic moiety, M?+x is a pharmaceutically acceptable cation and the compound decomposes under physiological conditions to release nitric oxide (NO). Compositions anti-hypertensives et procédé d'abaissement de la pression sanguine chez des mammifères. Le composant actif de la composition est un composé de la formule (I), dans laquelle J représente une fraction organique ou inorganique, M+x représente un cation pharmaceutiquement acceptable, et le composé se décompose dans des conditions physiologiques afin de libérer de l'oxyde nitrique (ON).