MOUSE MONOCLONAL ANTIBODIES RAISED TO THE T-CELL LINE HSB-2 AND T-CELL CHRONIC LYMPHOCYTIC LEUKEMIA (T-CLL) CELLS REACT WITH NORMAL HUMAN T AND B LYMPHOCYTES AND MONOCYTES

The prevent invention relates to two monoclonal antibodies which are broadly reactive with all normal human peripheral blood T and B lymphocytes and monocytes and to hybridoma cell lines which produce these monoclonal antibodies. These monoclonal antibodies are designated WM-66 and WM-63 and the res...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	HENNIKER, ANTHONY, JON, BRADSTOCK, KENNETH, FRANCIS, ATKINSON, MICHAEL, KERRY
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The prevent invention relates to two monoclonal antibodies which are broadly reactive with all normal human peripheral blood T and B lymphocytes and monocytes and to hybridoma cell lines which produce these monoclonal antibodies. These monoclonal antibodies are designated WM-66 and WM-63 and the respective hybridoma cell lines are designated F56-2D7 (ECAC 88101104) and F56-4D6 (ECACC 88101103). Both of these monoclonal antibodies react with a previously unrecognised human leucocyte differentiation antigen. The relative molecular mass of the antigen recognised by WM-66 is approximately 65 kilodaltons. La présente invention se rapporte à deux anticorps monoclonaux qui réagissent largement avec tous les monocytes et les lymphocytes T et B normaux de sang périphérique de l'homme, ainsi qu'à des lignées cellulaires d'hybridomes produisant ces anticorps monoclonaux. Ces anticorps monoclonaux sont appelés WM-66 et WM-63 et les lignées cellulaires d'hybridomes respectives sont appelées F56-2D7 (ECAC 88101104) et F56-4D6 (ECACC 88101103). Ces anticorps monoclonaux réagissent tous les deux avec un antigène de différenciation de leucocytes humains auparavant non reconnu. La masse moléculaire relative de l'antigène appelé WM-66 est approximativement de 65 kilodaltons.