1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES

1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES

The perhydrindoles of formula I, wherein R4? represents hydrogen or lower alkyl; R5? represents lower alkyl; or R5? represents lower alkyl substituted by optionally substituted phenyl; t is 0 or 1; esters, amides and salts thereof, are useful as antihypertensive and cardioactive agents. Perhydroindo...

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Bibliographische Detailangaben
1. Verfasser: GRUENFELD, NORBERT
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The perhydrindoles of formula I, wherein R4? represents hydrogen or lower alkyl; R5? represents lower alkyl; or R5? represents lower alkyl substituted by optionally substituted phenyl; t is 0 or 1; esters, amides and salts thereof, are useful as antihypertensive and cardioactive agents. Perhydroindols correspondant à la formule (I), où R4 représente de l'hydrogène ou un alkyle inférieur; R5 représente un alkyle inférieur ou R5 représente un alkyle inférieur substitué par un phényle facultativement substitué; t vaut 0 ou 1. Ces composés, ainsi que leurs esters, leurs amides et leurs sels, sont utiles en tant qu'agents antihypertensifs et cardio-actifs.