GRAFT-MODIFIED MESOPOROUS SILICA, AND PREPARATION METHOD THEREFOR AND USE THEREOF

The present invention relates to the field of medical drugs, and discloses a graft-modified mesoporous silica, and a preparation method therefor and the use thereof. In the graft-modified mesoporous silica, a digestive enzyme inhibitor is grafted onto mesoporous silica, and the grafting rate thereof is at least 0.1% by weight, the pore diameter of the mesoporous silica is 2-200 nm, the combined action of the digestive enzyme inhibitor and the mesoporous silica can effectively reduce the activity of the digestive enzyme inhibitor in the gastrointestinal tract, and the large specific surface area of the mesoporous silica is beneficial for improving the utilization rate of the digestive enzyme inhibitor. La présente invention concerne le domaine des médicaments, et concerne une silice mésoporeuse modifiée par greffage, son procédé de préparation et son utilisation. Dans la silice mésoporeuse modifiée par greffage, un inhibiteur d'enzyme digestive est greffé sur de la silice mésoporeuse, et son taux de greffage e