A PROCESS OF PREPARATION OF AN ANTIBACTERIAL COMPOUND AND ITS INTERMEDIATES THEREOF

A PROCESS OF PREPARATION OF AN ANTIBACTERIAL COMPOUND AND ITS INTERMEDIATES THEREOF

The present disclosure provides a process of preparation of an antibacterial compound of Formula I, (S)-6-(5-(((2-(7-fluoro-l- methyl-2-oxo-l,2-dihydroquinolin-8-yl) ethyl) amino) methyl)-2- oxooxazolidin-3-yl)-2H-pyrazino[2,3-b] [1,4] oxazin-3(4H)-one formate salt. The present disclosure also provi...

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Bibliographische Detailangaben
Hauptverfasser: PEER MOHAMED, Shahul Hameed, TUMMA, Harikrishna, KAUSHIK KOTAKONDA, Harish
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure provides a process of preparation of an antibacterial compound of Formula I, (S)-6-(5-(((2-(7-fluoro-l- methyl-2-oxo-l,2-dihydroquinolin-8-yl) ethyl) amino) methyl)-2- oxooxazolidin-3-yl)-2H-pyrazino[2,3-b] [1,4] oxazin-3(4H)-one formate salt. The present disclosure also provides intermediates of the compound of Formula I and their preparation. The present disclosure further provides a process of preparation of compound of Formula I with improved yield and high purity. La présente divulgation propose un procédé de préparation d'un composé antibactérien de formule I, sel formiate (S)-6-(5-(((2-(7-fluoro-1-méthyl-2-oxo-1,2-dihydroquinoléin-8-yl) éthyl) amino) méthyl)-2-oxooxazolidin-3-yl)-2H-pyrazino[2,3-b] [1,4] oxazin-3(4H)-one. La présente divulgation propose également des intermédiaires du composé de formule I et leur préparation. La présente divulgation propose en outre un procédé de préparation d'un composé de formule I avec un rendement amélioré et une pureté élevée.