NOVEL 2-(L,8-DIETHYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL)-N-(2-(PIPERIDIN-1 YL)ETHYL)ACETAMIDE ETODOLAC DERIVATIVE AS A EUKARYOTIC ELONGATION FACTOR 2 KINASE (EEF2K) INHIBITOR FOR TARGETED CANCER THERAPY

NOVEL 2-(L,8-DIETHYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL)-N-(2-(PIPERIDIN-1 YL)ETHYL)ACETAMIDE ETODOLAC DERIVATIVE AS A EUKARYOTIC ELONGATION FACTOR 2 KINASE (EEF2K) INHIBITOR FOR TARGETED CANCER THERAPY

The invention relates to a compound derivative that can be used in the treatment of cancer and other diseases through the development of small molecules as eukaryotic elongation factor 2 kinase (eEF2K) enzyme inhibitors that are active in breast, pancreatic, brain, ovarian, lung, skin and blood canc...

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Bibliographische Detailangaben
Hauptverfasser: DURDAGI, Serdar, COMERT ONDER, Ferah, OZPOLAT, Bulent, AY, Mehmet, SIYAH, Pinar
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Zusammenfassung:The invention relates to a compound derivative that can be used in the treatment of cancer and other diseases through the development of small molecules as eukaryotic elongation factor 2 kinase (eEF2K) enzyme inhibitors that are active in breast, pancreatic, brain, ovarian, lung, skin and blood cancers. L'invention concerne un dérivé de composé qui peut être utilisé dans le traitement du cancer et d'autres maladies par le développement de petites molécules en tant qu'inhibiteurs d'enzyme du facteur 2 kinase d'allongement eucaryote (eEF2K) qui sont actifs dans les cancers du sein, du pancréas, du cerveau, de l'ovaire, du poumon, de la peau et du sang.