PROBIOTIC DESIGNED TO EXPRESS AND SECRETE AKKERMANSIA MUCINIPHILA TARS AND VECTOR FOR PRODUCING SAME

The present invention relates to: a transformed strain expressing and secreting Akkermansia muciniphila TARS (AmTARS); and a vector for producing same. More specifically, the present invention relates to an Escherichia coli Nissle 1917 (EcN) strain expressing AmTARS, a composition comprising same, a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	PARK, Shinhye, HWANG, Seungho, KIM, Myung Hee, KIM, Su Man
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to: a transformed strain expressing and secreting Akkermansia muciniphila TARS (AmTARS); and a vector for producing same. More specifically, the present invention relates to an Escherichia coli Nissle 1917 (EcN) strain expressing AmTARS, a composition comprising same, a novel vector for producing same, and an EcN transformation method using same. La présente invention concerne : une souche transformée exprimant et sécrétant Akkermansia muciniphila TARS (AmTARS) ; et un vecteur permettant sa production. Plus spécifiquement, la présente invention concerne une souche d'Escherichia coli Nissle 1917 (EcN) exprimant AmTARS, une composition la comprenant, un nouveau vecteur permettant sa production, et un procédé de transformation d'EcN l'utilisant. 본 발명은 아커만시아 뮤시니필라 TARS (AmTARS)를 발현 및 분비하는 형질전환 균주 및 이의 제조를 위한 벡터에 관한 것으로, 보다 상세하게는 AmTARS를 발현하는 Escherichia coli Nissle 1917 (EcN) 균주, 이를 포함하는 조성물 및 이의 제조를 위한 신규 벡터 및 이를 활용한 EcN 형질전환 방법에 관한 것이다.