HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4

Provided herein are compounds and compositions thereof for modulating IRAK4. In some embodiments, the compounds and compositions are provided for treatment of inflammatory or autoimmune diseases. L'invention concerne des composés et des compositions de ceux-ci pour moduler IRAK4. Dans certains...

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Bibliographische Detailangaben
Hauptverfasser:	RASMUSSON, Timothy Gordon, GORMISKY, Paul E, DAVIES, Geraint
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Provided herein are compounds and compositions thereof for modulating IRAK4. In some embodiments, the compounds and compositions are provided for treatment of inflammatory or autoimmune diseases. L'invention concerne des composés et des compositions de ceux-ci pour moduler IRAK4. Dans certains modes de réalisation, les composés et les compositions sont fournis pour le traitement de maladies inflammatoires ou auto-immunes.