DSCAM INHIBITORY NUCLEIC ACIDS AND METHODS OF USE THEREOF
The disclosure features compositions and methods for the treatment of a subject. Disclosed herein are inhibitory nucleic acid molecules that suppress the expression of Down Syndrome Cell Adhesion Molecule (DSCAM), as well as mammalian cells and compositions comprising such inhibitory nucleic acid mo...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The disclosure features compositions and methods for the treatment of a subject. Disclosed herein are inhibitory nucleic acid molecules that suppress the expression of Down Syndrome Cell Adhesion Molecule (DSCAM), as well as mammalian cells and compositions comprising such inhibitory nucleic acid molecules. Also provided are methods for treating a subject (e.g., a subject having degeneration of the optic nerve (e.g., glaucoma)) with the compositions disclosed herein.
L'invention concerne des compositions et des procédés pour le traitement d'un sujet. L'invention concerne des molécules d'acides nucléiques inhibitrices qui suppriment l'expression de la molécule d'adhésion cellulaire du syndrome de Down (DSCAM), ainsi que des cellules de mammifère et des compositions comprenant de telles molécules d'acides nucléiques inhibitrices. L'invention concerne également des procédés de traitement d'un sujet (par exemple, d'un sujet ayant une dégénérescence du nerf optique (par exemple, un glaucome)) avec les compositions de l'invention. |
|---|