TREATMENT OF CANCER WITH A MEK KINASE INHIBITOR
Provided herein are compositions and methods for the treatment of cancer. Said compositions comprise a MEK kinase inhibitor that is 4-(dimethylphosphoryl)-N-(2-fluoro-4-iodophenyl)pyridin-3-amine (also known as KIN-7136). Some embodiments comprise combination therapy featuring the MEK kinase inhibit...
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| creator | GRANDINETTI, Kathryn B SURIBEN, Rowena QUAH, Cheng POWELL, Benjamin WILLIAMS, Richard Thomas COX, Jason M KANIA, Robert S MILLER, Nichol L.G |
| description | Provided herein are compositions and methods for the treatment of cancer. Said compositions comprise a MEK kinase inhibitor that is 4-(dimethylphosphoryl)-N-(2-fluoro-4-iodophenyl)pyridin-3-amine (also known as KIN-7136). Some embodiments comprise combination therapy featuring the MEK kinase inhibitor with at least one additional oncology therapeutic agent.
L'invention concerne des composés et des méthodes pour le traitement du cancer. Lesdites compositions comprennent un inhibiteur de MEK kinase qui est la 4-(diméthylphosphoryl)-N-(2-fluoro-4-iodophényl)pyridin-3-amine (également connue sous le nom de KIN-7136). Certains modes de réalisation comprennent une polythérapie comprenant l'inhibiteur de MEK kinase avec au moins un agent thérapeutique oncologique supplémentaire. |
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L'invention concerne des composés et des méthodes pour le traitement du cancer. Lesdites compositions comprennent un inhibiteur de MEK kinase qui est la 4-(diméthylphosphoryl)-N-(2-fluoro-4-iodophényl)pyridin-3-amine (également connue sous le nom de KIN-7136). Certains modes de réalisation comprennent une polythérapie comprenant l'inhibiteur de MEK kinase avec au moins un agent thérapeutique oncologique supplémentaire.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241024&DB=EPODOC&CC=WO&NR=2024220427A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241024&DB=EPODOC&CC=WO&NR=2024220427A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GRANDINETTI, Kathryn B</creatorcontrib><creatorcontrib>SURIBEN, Rowena</creatorcontrib><creatorcontrib>QUAH, Cheng</creatorcontrib><creatorcontrib>POWELL, Benjamin</creatorcontrib><creatorcontrib>WILLIAMS, Richard Thomas</creatorcontrib><creatorcontrib>COX, Jason M</creatorcontrib><creatorcontrib>KANIA, Robert S</creatorcontrib><creatorcontrib>MILLER, Nichol L.G</creatorcontrib><title>TREATMENT OF CANCER WITH A MEK KINASE INHIBITOR</title><description>Provided herein are compositions and methods for the treatment of cancer. Said compositions comprise a MEK kinase inhibitor that is 4-(dimethylphosphoryl)-N-(2-fluoro-4-iodophenyl)pyridin-3-amine (also known as KIN-7136). Some embodiments comprise combination therapy featuring the MEK kinase inhibitor with at least one additional oncology therapeutic agent.
L'invention concerne des composés et des méthodes pour le traitement du cancer. Lesdites compositions comprennent un inhibiteur de MEK kinase qui est la 4-(diméthylphosphoryl)-N-(2-fluoro-4-iodophényl)pyridin-3-amine (également connue sous le nom de KIN-7136). Certains modes de réalisation comprennent une polythérapie comprenant l'inhibiteur de MEK kinase avec au moins un agent thérapeutique oncologique supplémentaire.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAPCXJ1DPF19QtR8HdTcHb0c3YNUgj3DPFQcFTwdfVW8Pb0cwx2VfD08_B08gzxD-JhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGRiZGRgYmRuaOhsbEqQIAd30mig</recordid><startdate>20241024</startdate><enddate>20241024</enddate><creator>GRANDINETTI, Kathryn B</creator><creator>SURIBEN, Rowena</creator><creator>QUAH, Cheng</creator><creator>POWELL, Benjamin</creator><creator>WILLIAMS, Richard Thomas</creator><creator>COX, Jason M</creator><creator>KANIA, Robert S</creator><creator>MILLER, Nichol L.G</creator><scope>EVB</scope></search><sort><creationdate>20241024</creationdate><title>TREATMENT OF CANCER WITH A MEK KINASE INHIBITOR</title><author>GRANDINETTI, Kathryn B ; SURIBEN, Rowena ; QUAH, Cheng ; POWELL, Benjamin ; WILLIAMS, Richard Thomas ; COX, Jason M ; KANIA, Robert S ; MILLER, Nichol L.G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024220427A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GRANDINETTI, Kathryn B</creatorcontrib><creatorcontrib>SURIBEN, Rowena</creatorcontrib><creatorcontrib>QUAH, Cheng</creatorcontrib><creatorcontrib>POWELL, Benjamin</creatorcontrib><creatorcontrib>WILLIAMS, Richard Thomas</creatorcontrib><creatorcontrib>COX, Jason M</creatorcontrib><creatorcontrib>KANIA, Robert S</creatorcontrib><creatorcontrib>MILLER, Nichol L.G</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GRANDINETTI, Kathryn B</au><au>SURIBEN, Rowena</au><au>QUAH, Cheng</au><au>POWELL, Benjamin</au><au>WILLIAMS, Richard Thomas</au><au>COX, Jason M</au><au>KANIA, Robert S</au><au>MILLER, Nichol L.G</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TREATMENT OF CANCER WITH A MEK KINASE INHIBITOR</title><date>2024-10-24</date><risdate>2024</risdate><abstract>Provided herein are compositions and methods for the treatment of cancer. Said compositions comprise a MEK kinase inhibitor that is 4-(dimethylphosphoryl)-N-(2-fluoro-4-iodophenyl)pyridin-3-amine (also known as KIN-7136). Some embodiments comprise combination therapy featuring the MEK kinase inhibitor with at least one additional oncology therapeutic agent.
L'invention concerne des composés et des méthodes pour le traitement du cancer. Lesdites compositions comprennent un inhibiteur de MEK kinase qui est la 4-(diméthylphosphoryl)-N-(2-fluoro-4-iodophényl)pyridin-3-amine (également connue sous le nom de KIN-7136). Certains modes de réalisation comprennent une polythérapie comprenant l'inhibiteur de MEK kinase avec au moins un agent thérapeutique oncologique supplémentaire.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TREATMENT OF CANCER WITH A MEK KINASE INHIBITOR |
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