SOLID FORMS OF AN ENZYME INHIBITOR AND SALTS THEREOF

New solid forms of the Factor XIIa (FXIIa) inhibitor (R)-N5-((4-methyl-6-(6-methyl-3-(trifluoromethyl)- 5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)pyridin-3-yl)methyl)isoquinoline-1,5-diamine and its salts, are described. L'invention concerne de nouvelles formes solides de l'inhibi...

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Hauptverfasser: GORSUCH, Stephen, NORTHEN, Julian Scott, CECIL, Alexander Richard Liam, SPOONER, Calum James, MOORE, Gillian
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:New solid forms of the Factor XIIa (FXIIa) inhibitor (R)-N5-((4-methyl-6-(6-methyl-3-(trifluoromethyl)- 5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)pyridin-3-yl)methyl)isoquinoline-1,5-diamine and its salts, are described. L'invention concerne de nouvelles formes solides de l'inhibiteur du facteur XIIa (FXIIa) (R)-N5-((4-méthyl-6-(6-méthyl-3-(trifluorométhyl)-5,6-dihydro-[1,2,4] triazolo[4,3-a]pyrazin-7(8H)-yl)pyridin-3-yl)méthyl)isoquinoline-1,5-diamine et ses sels.