5-[5-(2-HYDROXYPHENYL)OXAZOLO[4,5-B]PYRIDIN-2-YL]PIPERIDIN-2-ONE DERIVATIVES AS NLPR3 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES

5-[5-(2-HYDROXYPHENYL)OXAZOLO[4,5-B]PYRIDIN-2-YL]PIPERIDIN-2-ONE DERIVATIVES AS NLPR3 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES

The invention relates to novel compounds having the general formula (I), wherein R1, R2, R9, A1, Y1, Y2 and Z are as described herein, composition including the compounds and methods of using the compounds. L'invention concerne de nouveaux composés de formule générale (I), dans laquelle R1, R2,...

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Bibliographische Detailangaben
Hauptverfasser: JAESCHKE, Georg, TOSSTORFF, Andreas Michael, HERR, Sabrina, STEINER, Sandra, SCHNIDER, Christian, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina, SHANNON, Jonathan Martin
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The invention relates to novel compounds having the general formula (I), wherein R1, R2, R9, A1, Y1, Y2 and Z are as described herein, composition including the compounds and methods of using the compounds. L'invention concerne de nouveaux composés de formule générale (I), dans laquelle R1, R2, R9, A1, Y1, Y2 et Z sont tels que définis dans la description, une composition comprenant ces composés et des procédés d'utilisation de ces composés.