OXAZOLO[4,5-B]PYRAZINE AND OXAZOLO[4,5-B]PYRIDINE DERIVATIVES AS NLRP3 INHIBITORS FOR THE TREATMENT OF E.G. INFLAMMATORY DISEASES

OXAZOLO[4,5-B]PYRAZINE AND OXAZOLO[4,5-B]PYRIDINE DERIVATIVES AS NLRP3 INHIBITORS FOR THE TREATMENT OF E.G. INFLAMMATORY DISEASES

The present invention relates to compounds of formula (I), which are NLRP3 inhibitors (NOD-like receptor pyrin domain-containing protein 3) for the treatment of e.g. inflammatory diseases. La présente invention concerne des composés de formule (I), qui sont des inhibiteurs de NLRP3 (protéine 3 conte...

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Hauptverfasser: JAESCHKE, Georg, TOSSTORFF, Andreas Michael, PATINY-ADAM, Angélique, STEINER, Sandra, SCHNIDER, Christian, BOUCHE, Lea Aurelie, GUBA, Wolfgang, BON, David, MESCH, Stefanie Katharina, SHANNON, Jonathan Martin
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to compounds of formula (I), which are NLRP3 inhibitors (NOD-like receptor pyrin domain-containing protein 3) for the treatment of e.g. inflammatory diseases. La présente invention concerne des composés de formule (I), qui sont des inhibiteurs de NLRP3 (protéine 3 contenant un domaine pyrine de récepteur de type NOD) pour le traitement, par exemple, de maladies inflammatoires.