RNA FOR PREVENTING OR TREATING TUBERCULOSIS

The disclosure provides agents and methods for preventing or treating tuberculosis using RNA. The RNA encoding antigens of Mycobacterium tuberculosis, immunogenic variants or fragments thereof is formulated and administered in a way that the antigens, variants or fragments are produced by cells of a...

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Bibliographische Detailangaben
Hauptverfasser:	MACARY, Paul Anthony, HOFFMANN, Sandro, ATES, Louis Simon, UEBELE, Julia, JAVID, Babak, DULBERGER, Charles Lefco
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The disclosure provides agents and methods for preventing or treating tuberculosis using RNA. The RNA encoding antigens of Mycobacterium tuberculosis, immunogenic variants or fragments thereof is formulated and administered in a way that the antigens, variants or fragments are produced by cells of a subject. La divulgation concerne des agents et des méthodes de prévention ou de traitement de la tuberculose à l'aide d'ARN. L'ARN codant pour des antigènes de Mycobacterium tuberculosis, des variants immunogènes ou des fragments de ceux-ci est formulé et administré de telle sorte que les antigènes, variants ou fragments sont produits par des cellules d'un sujet.