MASKING POLYPEPTIDES, ACTIVATABLE CYTOKINE CONSTRUCTS, AND RELATED COMPOSITIONS AND METHODS

Provided herein are activatable cytokine constructs that include a novel masking moiety, a cytokine polypeptide, and a cleavable moiety between the masking moiety and the cytokine polypeptide. In some embodiments, the ACC is a monomer. In some embodiments, the ACC is a complex of two, three, four, o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	PAIDHUNGAT, Madan M, KUMAR, Pankaj, LE SCOLAN, Erwan, DANIEL, Dylan L, CAI, Na
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!