FORMULATIONS FOR OLIGONUCLEOTIDE DELIVERY

The disclosure relates to compositions and methods for delivery of nucleic acid therapeutics, particularly iRNA agents to target locations and genes residing in the central nervous system (CNS) of a subject. L'invention concerne des compositions et des méthodes permettant la délivrance d'a...

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Bibliographische Detailangaben
Hauptverfasser:	YUEH, Han, SIMANI, Kamran, KRETSCHMER, Matthias, PHUNG, Andy, NECHEV, Lubomir, ZHANG, Ligang, JIANG, Liuwei, PANG, Bo, SHEN, Gang
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The disclosure relates to compositions and methods for delivery of nucleic acid therapeutics, particularly iRNA agents to target locations and genes residing in the central nervous system (CNS) of a subject. L'invention concerne des compositions et des méthodes permettant la délivrance d'agents thérapeutiques à base d'acides nucléiques, en particulier d'agents ARNi, à des emplacements cibles et des gènes résidant dans le système nerveux central (SNC) d'un sujet.