IRAK4 PROTACS

This specification relates to compounds according to Formula (I), which are of PROTACs of IRAK4, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of IRAK4-mediated and/or IRAK-4 directed diseases and disorders (IA) La présente invention concerne des compo...

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Bibliographische Detailangaben
Hauptverfasser:	TERSTIEGE, Ina, GARRISON, Aaron Thomas, MURPHY, John Joseph, KWAPIEŃ, Karolina
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This specification relates to compounds according to Formula (I), which are of PROTACs of IRAK4, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of IRAK4-mediated and/or IRAK-4 directed diseases and disorders (IA) La présente invention concerne des composés selon la formule (I), qui sont des PROTAC d'IRAK4, des compositions pharmaceutiques les contenant, et leur utilisation en thérapie pour le traitement de maladies et de troubles médiés par IRAK4 et/ou dirigés contre IRAK-4 (IA).