REAGENTS AND METHODS FOR IMAGING CANCERS EXPRESSING PDGFRALPHA

The invention relates to reagents for in vivo imaging and detection of cancers that express platelet derived growth factor receptor alpha (PDGFRalpha) using an olaratumab antibody, and methods of use thereof including methods for imaging cancers and methods for selecting patients for treatment. L�...

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Bibliographische Detailangaben
Hauptverfasser:	WHEATCROFT, Michael Paul, IVASHKEVICH, Alesia, PATEL, Neel Jagdish, HICKS, Rodney John, HONG, Angela Man Yin, BROWN, Tracey Jean, LETENDRE, Corinne
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	The invention relates to reagents for in vivo imaging and detection of cancers that express platelet derived growth factor receptor alpha (PDGFRalpha) using an olaratumab antibody, and methods of use thereof including methods for imaging cancers and methods for selecting patients for treatment. L'invention concerne des réactifs pour l'imagerie et la détection in vivo de cancers qui expriment le récepteur alpha du facteur de croissance dérivé des plaquettes (PDGFRalpha) à l'aide d'un anticorps olaratumab, et des procédés d'utilisation de ceux-ci comprenant des procédés d'imagerie de cancers et des procédés de sélection de patients pour le traitement.