HUMANIZED ANTI-TREM2 ANTIBODIES

This disclosure is related to humanized anti-TRE2 antibodies, TREM2-binding fragments and derivatives thereof, nucleic acids, and hosts cells expressing those antibodies and their use in immunotherapy for the treatment of cancer. In some embodiments, said compounds may be used for cancer treatment,...

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Bibliographische Detailangaben
Hauptverfasser:	SOLOMON, Noam, MAAMARY, Jad
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This disclosure is related to humanized anti-TRE2 antibodies, TREM2-binding fragments and derivatives thereof, nucleic acids, and hosts cells expressing those antibodies and their use in immunotherapy for the treatment of cancer. In some embodiments, said compounds may be used for cancer treatment, diagnostics, protein purification, and the like. La présente invention concerne des anticorps anti-TRE2 humanisés, des fragments de liaison à TREM2 et des dérivés de ceux-ci, des acides nucléiques, et des cellules hôtes exprimant ces anticorps et leur utilisation en immunothérapie pour le traitement du cancer. Dans certains modes de réalisation, lesdits composés peuvent être utilisés pour le traitement du cancer, le diagnostic, la purification de protéines et analogues.