MICROTUBULE-ASSOCIATED PROTEIN TAU TARGETING SIRNAS AND USES THEREOF

The present disclosure relates to siRNA, which target MAPT transcript in a cell, leading to reduced expression of MAPT protein. Reduction of MAPT protein expression is beneficial for the treatment of certain medical disorders, e.g., a tauopathy. La présente invention concerne un ARNsi qui cible un t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	KIM, Insun, KIM, Jihye, RYU, Jin-Hyeob, PARK, Suhyeong, KWON, Mincheol, PARK, Young Jin, LIM, Yu Na
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present disclosure relates to siRNA, which target MAPT transcript in a cell, leading to reduced expression of MAPT protein. Reduction of MAPT protein expression is beneficial for the treatment of certain medical disorders, e.g., a tauopathy. La présente invention concerne un ARNsi qui cible un transcrit MAPT dans une cellule, conduisant à une expression réduite de la protéine MAPT. La réduction de l'expression de la protéine MAPT est bénéfique pour le traitement de certains troubles médicaux, par exemple, une tauopathie.