NECTIN-4 BINDING AGENTS AND METHODS OF USE

Provided herein are Nectin-4 binding agents, multi-specific binding agents thereof, polynucleotides encoding the same, and compositions comprising the same. The present disclosure further provides methods of treating cancer in a subject in need thereof comprising administration of the Nectin-4 bindi...

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Hauptverfasser: LUTJE HULSIK, David, VAN HELDEN, Paula Maria Wilhelmina, DE JONG, Milon, SALLER, Manfred, VAN DER VLIET, Johannes Jelle, ADANG, Anton Egbert Peter, ROOVERS, Robertus Cornelis
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creator LUTJE HULSIK, David
VAN HELDEN, Paula Maria Wilhelmina
DE JONG, Milon
SALLER, Manfred
VAN DER VLIET, Johannes Jelle
ADANG, Anton Egbert Peter
ROOVERS, Robertus Cornelis
description Provided herein are Nectin-4 binding agents, multi-specific binding agents thereof, polynucleotides encoding the same, and compositions comprising the same. The present disclosure further provides methods of treating cancer in a subject in need thereof comprising administration of the Nectin-4 binding agents and multi-specific binding agents comprising the same to a subject in need thereof. La présente invention concerne des agents de liaison à la nectine -4, des agents de liaison multi-spécifiques de ceux-ci, des polynucléotides codant pour ceux-ci, et des compositions les comprenant. La présente invention concerne en outre des méthodes de traitement du cancer chez un sujet dont l'état le nécessite, consistant en l'administration des agents de liaison à la nectine-4 et d'agents de liaison multi-spécifiques les comprenant à un sujet dont l'état le nécessite.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NECTIN-4 BINDING AGENTS AND METHODS OF USE
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