NOVEL CHOLIC ACID DERIVATIVE AND USE THEREOF

The present invention relates to a novel cholic acid derivative synthesized from lithocholic acid or chenodeoxycholic acid, and use thereof. The cholic acid derivative can be used as a candidate or intermediate for drug development. In addition, according to the present, the cholic acid derivative o...

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Bibliographische Detailangaben
Hauptverfasser:	MOON, Hye Jin, KIM, Hak Won, LEE, Tae Hoon, YOON, Do Won, KIM, Jung Wook
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	CHEMISTRY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a novel cholic acid derivative synthesized from lithocholic acid or chenodeoxycholic acid, and use thereof. The cholic acid derivative can be used as a candidate or intermediate for drug development. In addition, according to the present, the cholic acid derivative or a salt thereof can be used for: a pharmaceutical use for prevention or treatment of inflammatory diseases; or a functional food use for alleviation of inflammatory diseases. La présente invention concerne un nouveau dérivé d'acide cholique synthétisé à partir d'acide lithocholique ou d'acide chénodésoxycholique, et son utilisation. Le dérivé d'acide cholique peut être utilisé comme candidat ou intermédiaire pour le développement de médicaments. De plus, selon l'invention, le dérivé d'acide cholique ou un sel de celui-ci peut être utilisé pour : une utilisation pharmaceutique pour la prévention ou le traitement de maladies inflammatoires ; ou une utilisation alimentaire fonctionnelle pour le soulagement de maladies inflammatoires. 본 발명은 리토콜산 또는 케노디옥시콜산으로부터 합성된 신규한 콜린산 유도체 및 이의 용도에 관한 것이다. 상기 콜린산 유도체는 의약품 개발의 후보물질 또는 중간체로 사용될 수 있다. 또한, 본 발명에 따르면 상기 콜린산 유도체 또는 이의 염은 염증성 질환의 예방 또는 치료를 위한 약학적 용도 또는 염증성 질환의 개선을 위한 기능성 식품용 용도로 사용될 수 있다.