CELLS AND METHODS OF PREPARATION

A method of preparing cells for therapeutic use is provided, in which a population of progenitor cells is cultured in cell culture conditions that promote differentiation of the progenitor cells comprising the presence of: G-CSF, GM-CSF, IL-3 and TNF; to produce a population of granulopoietic cells....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MCGINLEY, Aoife, POLYAKOVA, Oxana, PATEL, Mihil, WILLIS, Andrew, FLORENCE, Samuel, BLYTH, Alex, PATEL, Durva
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A method of preparing cells for therapeutic use is provided, in which a population of progenitor cells is cultured in cell culture conditions that promote differentiation of the progenitor cells comprising the presence of: G-CSF, GM-CSF, IL-3 and TNF; to produce a population of granulopoietic cells. The granulopoietic cells produced may be useful in methods of treatment, including the treatment of cancer and infections, and to modulate inflammatory cell responses. L'invention concerne un procédé de préparation de cellules à usage thérapeutique, dans lequel une population de cellules progénitrices est cultivée dans des conditions de culture cellulaire qui favorisent la différenciation des cellules progénitrices comprenant la présence de : G-CSF, GM-CSF, IL-3 et TNF; pour produire une population de cellules granulopoïétiques. Les cellules granulopoïétiques produites peuvent être utiles dans des procédés de traitement, y compris le traitement du cancer et d'infections, et pour moduler des réponses de cellules inflammatoires.