PULMONARY TUBERCULOSIS VACCINE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Provided is an immunogenic composition, the immunogenic composition comprising one or more pulmonary tuberculosis antigens. After performing mucosal immunization on the body via inhalation, the invention not only has a high level of specific antibodies targeting mycobacterium tuberculosis simultaneo...

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Hauptverfasser: XU, Fang, ZHAO, Xiaolong, SI, Weixue, ZHU, Tao, SHAO, Juan, PENG, Shaodan, TANG, Xue, MIAO, Wei
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creator XU, Fang
ZHAO, Xiaolong
SI, Weixue
ZHU, Tao
SHAO, Juan
PENG, Shaodan
TANG, Xue
MIAO, Wei
description Provided is an immunogenic composition, the immunogenic composition comprising one or more pulmonary tuberculosis antigens. After performing mucosal immunization on the body via inhalation, the invention not only has a high level of specific antibodies targeting mycobacterium tuberculosis simultaneously generated in the lungs and body, but can also stimulate a very high cell immune response. L'invention concerne une composition immunogène, la composition immunogène comprenant un ou plusieurs antigènes de tuberculose pulmonaire. Après avoir effectué une immunisation des muqueuses sur le corps par inhalation, l'invention a non seulement un niveau élevé d'anticorps spécifiques ciblant mycobacterium tuberculosis généré simultanément dans les poumons et le corps, mais peut également stimuler une réponse immunitaire cellulaire très élevée. 提供了一种免疫原性组合物,免疫原性组合物包括一种或多种肺结核抗原。在对机体进行吸入黏膜免疫后,不仅可以同时在肺部和机体内产生针对结核分枝杆菌的高水平特异性抗体,还可以刺激产生很高的细胞免疫反应。
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language chi ; eng ; fre
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title PULMONARY TUBERCULOSIS VACCINE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
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