PULMONARY TUBERCULOSIS VACCINE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Provided is an immunogenic composition, the immunogenic composition comprising one or more pulmonary tuberculosis antigens. After performing mucosal immunization on the body via inhalation, the invention not only has a high level of specific antibodies targeting mycobacterium tuberculosis simultaneo...

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Bibliographische Detailangaben
Hauptverfasser:	XU, Fang, ZHAO, Xiaolong, SI, Weixue, ZHU, Tao, SHAO, Juan, PENG, Shaodan, TANG, Xue, MIAO, Wei
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided is an immunogenic composition, the immunogenic composition comprising one or more pulmonary tuberculosis antigens. After performing mucosal immunization on the body via inhalation, the invention not only has a high level of specific antibodies targeting mycobacterium tuberculosis simultaneously generated in the lungs and body, but can also stimulate a very high cell immune response. L'invention concerne une composition immunogène, la composition immunogène comprenant un ou plusieurs antigènes de tuberculose pulmonaire. Après avoir effectué une immunisation des muqueuses sur le corps par inhalation, l'invention a non seulement un niveau élevé d'anticorps spécifiques ciblant mycobacterium tuberculosis généré simultanément dans les poumons et le corps, mais peut également stimuler une réponse immunitaire cellulaire très élevée. 提供了一种免疫原性组合物，免疫原性组合物包括一种或多种肺结核抗原。在对机体进行吸入黏膜免疫后，不仅可以同时在肺部和机体内产生针对结核分枝杆菌的高水平特异性抗体，还可以刺激产生很高的细胞免疫反应。