HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS

The present application provides heterocyclic compounds that modulate the activity of Werner syndrome helicase (WRN), and are useful in the treatment of various diseases, including cancer. La présente invention concerne des composés hétérocycliques qui modulent l'activité de l'hélicase du...

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Bibliographische Detailangaben
Hauptverfasser:	MUKAI, Ken, YANG, Jeffrey, YOU, Lin, ZHANG, Fenglei, QI, Chao, ZHOU, Fei, HE, Chunhong, YAO, Wenqing, ZHENG, Hewen, LI, Yu, WU, Liangxing, BAI, Yu
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application provides heterocyclic compounds that modulate the activity of Werner syndrome helicase (WRN), and are useful in the treatment of various diseases, including cancer. La présente invention concerne des composés hétérocycliques qui modulent l'activité de l'hélicase du syndrome de Werner (WRN), et sont utiles dans le traitement de diverses maladies, y compris le cancer.