COMPOSITION COMPRISING MAST CELL-CONDITIONED MEDIUM FOR WOUND HEALING

The present invention relates to a composition for skin wound healing, comprising a mast cell-conditioned medium as an active ingredient. A mast cell-conditioned medium or a conditioned medium of mast cells stimulated with toll-like receptor 2 and 6 agonists, of the present invention, has the effect...

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Bibliographische Detailangaben
Hauptverfasser:	KWON, Jiyun, WOO, So-Youn, CHO, Kyung-Ah
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a composition for skin wound healing, comprising a mast cell-conditioned medium as an active ingredient. A mast cell-conditioned medium or a conditioned medium of mast cells stimulated with toll-like receptor 2 and 6 agonists, of the present invention, has the effect of promoting cell migration of human dermal keratinocytes and exhibits an excellent treatment effect during wound healing, especially in the inflammatory phase. La présente invention concerne une composition pour la cicatrisation de plaies cutanées, comprenant un milieu conditionné par des mastocytes en tant que principe actif. Un milieu conditionné par des mastocytes ou un milieu conditionné de mastocytes stimulés par des agonistes du récepteur de type Toll 2 et 6, de la présente invention, a pour effet de favoriser la migration cellulaire des kératinocytes dermiques humains et présente un excellent effet de traitement pendant la cicatrisation des plaies, en particulier dans la phase inflammatoire. 본 발명은 비만세포의 조정배지를 유효성분으로 포함하는 피부 창상 치료용 조성물에 관한 것이다. 본 발명의 비만세포 조정배지 또는 톨 유사 수용체 2와 6 작용제로 자극된 비만세포 조정배지는 사람 피부 각질세포의 세포이동을 촉진시키는 효과를 가지며, 창상 치유 과정 중 특히 염증 단계에서 우수한 치료 효과를 나타낸다.