KRAS INHIBITORS

The present disclosure relates to compounds that inhibit KRAS. In particular, the present disclosure relates to compounds that inhibit the activity of KRAS G12D, pharmaceutical compositions comprising the compounds and methods of use therefor. La présente invention concerne des composés qui inhibent...

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Bibliographische Detailangaben
Hauptverfasser:	GAO, Yunlong, LI, Chao, LI, Liugen, CHEN, Jianyong, HU, Wenliang, YE, Gaojie
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure relates to compounds that inhibit KRAS. In particular, the present disclosure relates to compounds that inhibit the activity of KRAS G12D, pharmaceutical compositions comprising the compounds and methods of use therefor. La présente invention concerne des composés qui inhibent KRAS. En particulier, la présente invention concerne des composés qui inhibent l'activité de KRAS G12D, des compositions pharmaceutiques comprenant ces composés et des procédés d'utilisation associés.