CANNABIDIOL-ANTIMICROBIAL PEPTIDE AND APPLICATION THEREOF

Provided are a cannabidiol-antimicrobial peptide and an application thereof. The cannabidiol-antimicrobial peptide is obtained by coupling an antimicrobial peptide with cannabidiol by means of a linker. The cannabidiol-antimicrobial peptide has good antibacterial effects on Staphylococcus aureus, Ps...

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Bibliographische Detailangaben
Hauptverfasser:	DU, Haiyu, YOU, Zhiliang, LI, Qingyang, YIN, Chuanlong, ZOU, Weixing, TANG, Renjin, TANG, Xiaoming, OU, Yangjie, HE, Yonghua
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are a cannabidiol-antimicrobial peptide and an application thereof. The cannabidiol-antimicrobial peptide is obtained by coupling an antimicrobial peptide with cannabidiol by means of a linker. The cannabidiol-antimicrobial peptide has good antibacterial effects on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. The antibacterial rate of the cannabidiol-antimicrobial peptide with a concentration of 10 μg/ml on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans reaches 45.8% to 100%. Compared with separate use of cannabidiol and the antimicrobial peptide, the cannabidiol-antimicrobial peptide has significantly improved antibacterial effects on Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli, providing a new option for antibacterial and bacteriostatic purposes. L'invention concerne un peptide antimicrobien de cannabidiol et son utilisation. Le peptide antimicrobien de cannabidiol est obtenu par couplage d'un p