RGD-CONTAINING PEPTIDES FOR DELIVERING PAYLOADS

The present disclosure pertains to muscle-targeting moieties comprising RGD- containing peptides which peptides can be inserted in the capsid of a recombinant adeno- associated virus (rAAV) vector. Also disclosed herein are compositions comprising muscle- targeting moieties disclosed herein and meth...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN, Wei Tong, CACHORRO, Adelaida Palla, PARMENTIER-BATTEUR, Anne-Sophie, HUNG, Ka Ying, SPARROW, Junghae Suh, JIN, Quan, DESMARAIS, Samantha, YUAN, Yuan
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure pertains to muscle-targeting moieties comprising RGD- containing peptides which peptides can be inserted in the capsid of a recombinant adeno- associated virus (rAAV) vector. Also disclosed herein are compositions comprising muscle- targeting moieties disclosed herein and methods of making and using the same. La présente divulgation concerne des fractions de ciblage musculaire comprenant des peptides contenant RGD qui peuvent être insérés dans la capside d'un vecteur de virus adéno-associé recombinant (rAAV). Sont également divulgués dans la description des compositions comprenant des fractions de ciblage musculaire divulguées dans la description et des procédés de fabrication et d'utilisation de celles-ci.