HSC-SPECIFIC ANTIBODY CONJUGATED LIPID NANOPARTICLES AND USES THEREOF

Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., HSC), and methods of making and using such lipids and targeted lipid. nanoparticles. L'invention concerne des nanoparticules lipidiques et des lipides cationiques ionisables pour l&#...

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Hauptverfasser: BOESCH, Austin Wayne, DRUMMOND, Daryl Clark, HOPE, Jacob, BORGES, Christopher
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creator BOESCH, Austin Wayne
DRUMMOND, Daryl Clark
HOPE, Jacob
BORGES, Christopher
description Provided are ionizable cationic lipids and lipid nanoparticles for the delivery of nucleic acids to cells (e.g., HSC), and methods of making and using such lipids and targeted lipid. nanoparticles. L'invention concerne des nanoparticules lipidiques et des lipides cationiques ionisables pour l'administration d'acides nucléiques à des cellules (par exemple, des cellules souches hématopoïétiques, (CSH)), ainsi que des méthodes de fabrication et d'utilisation de tels lipides et nanoparticules lipidiques ciblées.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title HSC-SPECIFIC ANTIBODY CONJUGATED LIPID NANOPARTICLES AND USES THEREOF
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