SUBSTITUTED AZOLES AND THEIR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ALPHA- 1 -ANTITRYPSIN (A1AT) DEFICIENCY

The application is directed to compounds of Formula (I): (I), and their salts and solvates, wherein A1, A2, G, R1-R5, and n are as set forth in the specification, and their use in the treatment and/or prevention of disorders or diseases associated with alpha-1- antitrypsin (A1AT) deficiency. L'...

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Hauptverfasser:	GARCÍA COLLAZO, Ana Maria, CUBERO JORDÀ, Elena, TRAPERO PUIG, Ana
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	The application is directed to compounds of Formula (I): (I), and their salts and solvates, wherein A1, A2, G, R1-R5, and n are as set forth in the specification, and their use in the treatment and/or prevention of disorders or diseases associated with alpha-1- antitrypsin (A1AT) deficiency. L'invention concerne des composés de formule (I) : (I), et leurs sels et solvates, A1, A2, G, R1-R5, et n étant tels que définis dans la description, et leur utilisation dans le traitement et/ou la prévention de troubles ou de maladies associés à une déficience en alpha-1-antitrypsine (A1AT).