ANTIBODIES

The invention relates to antibodies or antigen-binding fragments thereof which specifically bind to CXCR4. The invention also relates to said antibodies for use in therapy, for use in treating cancer, and for use in treating a solid tumor. The invention also relates to pharmaceutical compositions co...

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Hauptverfasser: BENNETT, Kirstie, STOTT, Lisa, BILLAUD, Margot, ROWLANDS, Robert, LECOINTRE, Morgane Marie, WAKE, Matthew Stephen, MCCOURT, John Matthew, BARNES, Matthew, HUTCHINGS, Catherine
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creator BENNETT, Kirstie
STOTT, Lisa
BILLAUD, Margot
ROWLANDS, Robert
LECOINTRE, Morgane Marie
WAKE, Matthew Stephen
MCCOURT, John Matthew
BARNES, Matthew
HUTCHINGS, Catherine
description The invention relates to antibodies or antigen-binding fragments thereof which specifically bind to CXCR4. The invention also relates to said antibodies for use in therapy, for use in treating cancer, and for use in treating a solid tumor. The invention also relates to pharmaceutical compositions comprising said antibodies, nucleic acids that encode said antibodies, vectors comprising said nucleic acids, and host cells comprising said nucleic acids or vectors. L'invention concerne des anticorps ou des fragments de liaison à l'antigène de ceux-ci qui se lient spécifiquement à CXCR4. L'invention concerne également lesdits anticorps destinés à être utilisés en thérapie, dans le traitement du cancer et dans le traitement d'une tumeur solide. L'invention concerne en outre des compositions pharmaceutiques comprenant lesdits anticorps, des acides nucléiques qui codent lesdits anticorps, des vecteurs comprenant lesdits acides nucléiques et des cellules hôtes comprenant lesdits acides nucléiques ou vecteurs.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTIBODIES
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