N-SUBSTITUTED INDAZOLE SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS BACKGROUND

N-SUBSTITUTED INDAZOLE SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS BACKGROUND

The present disclosure is directed to compounds that are blockers of NaV1.7 which have the structure of Formula I: or a pharmaceutically acceptable salt thereof. La présente invention concerne des composés qui sont des agents de blocage de NaV1.7 et ont la structure de formule I : ou un sel pharmace...

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Bibliographische Detailangaben
Hauptverfasser: GILBERT, Kevin F, PERO, Joseph E, KELLY III, Michael J, LAYTON, Mark E
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure is directed to compounds that are blockers of NaV1.7 which have the structure of Formula I: or a pharmaceutically acceptable salt thereof. La présente invention concerne des composés qui sont des agents de blocage de NaV1.7 et ont la structure de formule I : ou un sel pharmaceutiquement acceptable de ceux-ci.