MICELLE NANOPARTICLES COMPRISING BIOPOLYMER-HEMIN COMPLEX, AND USE THEREOF

The present invention relates to micelle nanoparticles comprising a biopolymer-hemin complex, and a use thereof, and, more specifically, to micelle nanoparticles comprising a biopolymer-hemin complex, and a use thereof, the nanoparticles having a core-shell structure formed by the self-assembly of a...

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Bibliographische Detailangaben
Hauptverfasser: MIN, Ki Yoon, TAE, Gi Yoong, JEON, Sae Hyun, SAHU, Abhishek, JUNG, Jun Young
Format: Patent
Sprache:eng ; fre ; kor
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Zusammenfassung:The present invention relates to micelle nanoparticles comprising a biopolymer-hemin complex, and a use thereof, and, more specifically, to micelle nanoparticles comprising a biopolymer-hemin complex, and a use thereof, the nanoparticles having a core-shell structure formed by the self-assembly of a polymer-hemin complex in which a hydrophilic biopolymer and hydrophobic hemin are bound to each other, thereby having excellent catalase- and superoxide dismutase-like activities and effectively treating, alleviating or preventing inflammatory diseases. La présente invention concerne des nanoparticules de micelle comprenant un complexe biopolymère-hémine, et une utilisation de celles-ci, et, plus spécifiquement, des nanoparticules de micelle comprenant un complexe biopolymère-hémine, et une utilisation de celles-ci, les nanoparticules ayant une structure coeur-écorce formée par auto-assemblage d'un complexe polymère-hémine dans lequel un biopolymère hydrophile et une hémine hydrophobe sont liés l'un à l'autre, présentant ainsi d'excellentes activités de type catalase et superoxyde dismutase et traitant, soulageant ou prévenant efficacement des maladies inflammatoires. 본 발명은 바이오 폴리머-헤민 복합체를 포함하는 마이셀 나노입자 및 그의 용도에 관한 것으로서, 보다 상세하게는 친수성 바이오 폴리머와 소수성 헤민이 결합된 폴리머-헤민 복합체의 자가 조립에 의해 형성되는 코어-쉘 구조를 가짐으로써 과산화수소 분해효소 및 초과산화물 불균등화효소 유사 활성이 우수하고 염증성 질환의 치료, 개선 또는 예방 효과가 있는 바이오 폴리머-헤민 복합체를 포함하는 마이셀 나노입자 및 그의 용도에 관한 것이다.