COMPOUNDS FOR FGFRS INHIBITORS

A compound having the following structure of Formula (I): (I) or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R5, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described. L'inventio...

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Bibliographische Detailangaben
Hauptverfasser:	BETTENDORF, Tanna, CHATTERJEE, Payal, FULTON, Jennifer, SMITH, Aaron Christopher, DAHLKE, Joshua, MALINKY, Cori A, SCAGGS, Toya D, RODRIGUEZ, Martha E, MEJIA, Macedonio J, ROBINSON, John E, FISCHER, John P, NEWHOUSE, Bradley J, CHICARELLI, Mark Joseph, FELL, Jay Bradford, VINE, Logan E, RIEGER, Robert A, JALLURI, Ravi Kumar, SALITURO, Leah J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	A compound having the following structure of Formula (I): (I) or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R5, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described. L'invention concerne un composé ayant la structure suivante de formule (I) : (I) ou un stéréoisomère, un sel ou un tautomère de celui-ci, formule dans laquelle R1, R2, R5, A, B, X, et Y sont tels que définis dans la description. L'invention concerne également une composition pharmaceutique comprenant les composés, et leur utilisation dans des procédés permettant de traiter des maladies.