MUTANT AMINOACYL TRNA SYNTHETASE, COMPOSITIONS COMPRISING SAME, AND USE THEREOF

The present invention provides a protein including the amino acid sequence of SEQ ID NO: 7, wherein isoleucine at position 159 is substituted with Ser or Asp. Further provided are composition comprising the protein disclosed herein, as well as methods of using same, such as for producing a protein o...

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Bibliographische Detailangaben
Hauptverfasser:	STRUGACH, Daniela, AMIRAM, Miriam
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides a protein including the amino acid sequence of SEQ ID NO: 7, wherein isoleucine at position 159 is substituted with Ser or Asp. Further provided are composition comprising the protein disclosed herein, as well as methods of using same, such as for producing a protein of interest including a non-standard amino acid. La présente invention concerne une protéine comprenant la séquence d'acides aminés de SEQ ID NO : 7, l'isoleucine en position 159 étant substituée par Ser ou Asp. La présente invention porte également sur une composition comprenant la protéine de la présente invention, ainsi que sur des procédés d'utilisation de celle-ci, notamment pour la production d'une protéine d'intérêt comprenant un acide aminé non standard.