USE OF 5'-О-(3-PHENYLPROPIONYL)-N4-HYDROXYCYTIDINE TO INHIBIT INFLUENZA VIRUS REPLICATION IN VITRO AND IN VIVO

The invention relates to chemistry, pharmaceutics and medicine, and more particularly to the use of 5'-O-(3-phenylpropionyl)-N4-hydroxycytidine to inhibit replication of the influenza virus. The claimed invention provides for the use of a new ester derivative of N4-hydroxycytidine with carboxyl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	TEREKHOV, Aleksandr Aleksandrovich, LOGUNOV, Denis Iurevich, IVANOV, Igor Andreevich, BANDELIUK, Alina Sergeevna, BONDAREVA, Nataliia Evgenevna, TUKHVATULINA, Natalia Mikhailovna, SHEREMET, Anna Borisovna, SHIDLOVSKAIA, Elena Vladimirovna, TKACHUK, Artem Petrovich, REMIZOV, Timofei Andreevich, LUIKSAAR, Sergei Igorevich, VASINA, Daria Vladimirovna, RUSSU, Leonid Ivanovich, GINTSBURG, Aleksandr Leonidovich, LUBENETS, Nadezhda Leonidovna, INSHAKOVA, Anna Mikhailovna, ZIGANGIROVA, Nailia Akhatovna, SHMAROV, Maksim Mikhailovich, DARNOTUK, Elizaveta Sergeevna, KUZNETSOVA, Nadezhda Anatolevna, SOLOVEVA, Anna Vladimirovna, EVGRAFOVA, Elina Alekseevna, SINIAVIN, Andrei Eduardovich, ZAKHAROVA, Anastasiia Andreevna, GUSHCHIN, Vladimir Alekseevich, ZOLOTOV, Sergei Anatolievich, TOKARSKAIA, Elizaveta Aleksandrovna, SHASTINA, Natalia Sergeyevna, USACHEV, Evgenii Valerevich
Format:	Patent
Sprache:	eng ; fre ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to chemistry, pharmaceutics and medicine, and more particularly to the use of 5'-O-(3-phenylpropionyl)-N4-hydroxycytidine to inhibit replication of the influenza virus. The claimed invention provides for the use of a new ester derivative of N4-hydroxycytidine with carboxylic acid to inhibit replication of the influenza virus. L'invention se rapporte au domaine de la chimie, de la pharmacie et de la médecine, et concerne notamment l'utilisation de 5'-O-(3-phénylpropionyle)-N4-hydroxycytidine pour inhiber la réplication du virus de la grippe. La présente invention porte sur l'utilisation d'un nouveau dérivé à éther complexe de N-hydroxycytidine avec de l'acide carboxylique pour inhiber la réplication du virus de la grippe. Изобретение относится к химии, фармацевтике и медицине, а именно к применению 5'-O-(3-фенилпропионил)-N4-гидроксицитидина для ингибирования репликации вируса гриппа. Заявленное изобретение обеспечивает применение нового сложноэфирного производного N4-гидроксицитидина с карбоновой кислотой для ингибирования репликации вируса гриппа.