Novel process for the preparation of intermediate compounds used in the treatment of migraine

Novel process for the preparation of intermediate compounds used in the treatment of migraine

The present application relates to a process for the preparation of (S)-2'-oxo-1',2',5,7- tetrahydrospiro [cyclopenta[b] pyridine-6,3'-pyrrolo [2,3-b] pyridine]-3-carboxylic acid of formula-1, which is a key intermediate compounds for the preparation of Ubrogepant and Atogepant u...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: EPPA, Narayana, SAGYAM, Rajeshwar Reddy, VELISHALA, Praveen, SRINIVASAN, Thirumalai Rajan, SAJJA, Eswaraiah, GANGAJJI, Parameshwarappa
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present application relates to a process for the preparation of (S)-2'-oxo-1',2',5,7- tetrahydrospiro [cyclopenta[b] pyridine-6,3'-pyrrolo [2,3-b] pyridine]-3-carboxylic acid of formula-1, which is a key intermediate compounds for the preparation of Ubrogepant and Atogepant used in migraine treatment. The present invention also provides a novel intermediate compounds and their process for the preparation. La présente demande concerne une méthode de préparation d'acide (S)-2'-oxo-1', 2', 5,7-tétrahydrospiro [cyclopenta[b] pyridine -6,3'pyrrolo [2,3-b] pyridine]-3-carboxylique de formule 1, qui est un composé intermédiaire clé dans la préparation d'Ubrogepant et d'Atogepant utilisés dans le traitement de la migraine. La présente demande concerne également de nouveaux composés intermédiaires et leur méthodes de préparation.