CHEMICALLY MODIFIED SARNA COMPOSITIONS AND METHODS OF USE

The disclosure relates to a saRNA useful in upregulating the expression of a target gene and therapeutic compositions comprising the saRNA, wherein the saRNA is chemically modified. Methods of using the saRNA and the therapeutic compositions are also provided. L'invention concerne un ARNsa util...

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Bibliographische Detailangaben
Hauptverfasser:	PENDERGRAFF, Hannah, HANSEN, Henrik, KOCH, Troels, HAMMILL, Matthew, AGUTI, Sara, DESAULNIERS, Jean-Paul, GIORGEES, Ifrodet, HOARE, Joseph Ieuan
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The disclosure relates to a saRNA useful in upregulating the expression of a target gene and therapeutic compositions comprising the saRNA, wherein the saRNA is chemically modified. Methods of using the saRNA and the therapeutic compositions are also provided. L'invention concerne un ARNsa utile dans la régulation à la hausse de l'expression d'un gène cible et des compositions thérapeutiques comprenant l'ARNsa, l'ARNsa étant chimiquement modifié. L'invention concerne également des procédés d'utilisation de l'ARNsa et des compositions thérapeutiques.