PROTEASE INHIBITORS AND METHODS OF USING SAME

Inhibitors of the SARS-CoV-2 Mpro protease and methods of their use in treating a coronavirus infection in a subject are provided. The inhibitors may have the general structure (I) : L'invention concerne des inhibiteurs de la protéase Mpro du SARS-CoV-2 et des méthodes d'utilisation de ceu...

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Hauptverfasser:	KHODABANDEH, Mehran, GUZZO, Peter, ALPERSTEIN, Zaccary, ROLFE, Jason, SABERALI, Seyed Ali, MSLATI, Hazem
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Inhibitors of the SARS-CoV-2 Mpro protease and methods of their use in treating a coronavirus infection in a subject are provided. The inhibitors may have the general structure (I) : L'invention concerne des inhibiteurs de la protéase Mpro du SARS-CoV-2 et des méthodes d'utilisation de ceux-ci dans le traitement d'une infection à coronavirus chez un sujet. Les inhibiteurs peuvent avoir la structure générale (I).