COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF

Described herein are compounds of Formula I and their pharmaceutically acceptable salts, solvates, or stereoisomers thereof, as well as their uses (e.g., for degrading certain proteins such as p300/CBP proteins). L'invention concerne des composés de formule I et leurs solvates, stéréoisomères o...

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Bibliographische Detailangaben
Hauptverfasser:	THOMAS, Junius, ROACH, Jeremy, WANG, Shaomeng, PRIESTLEY, E, WANG, Mi, ZHANG, Xuqing, DENG, Qiaolin
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Described herein are compounds of Formula I and their pharmaceutically acceptable salts, solvates, or stereoisomers thereof, as well as their uses (e.g., for degrading certain proteins such as p300/CBP proteins). L'invention concerne des composés de formule I et leurs solvates, stéréoisomères ou sels pharmaceutiquement acceptables, ainsi que leurs utilisations (par exemple, pour dégrader certaines protéines telles que des protéines p300/CBP).