SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF

This disclosure provides compounds of Formula (1), compositions comprising the same, and methods of using the same, including uses in modulating SARM1 and treating various diseases and conditions, e.g., those caused by axonal degeneration. La présente divulgation concerne des composés de formule (1)...

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Bibliographische Detailangaben
Hauptverfasser:	JIANG, Ming, ZHANG, Zhaolan, WU, Jinbao, LIU, Yingtao, HAN, Jianguang, SUN, Zhen, SUN, Baochuan, XU, Yanping, LIU, Lianzhu
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This disclosure provides compounds of Formula (1), compositions comprising the same, and methods of using the same, including uses in modulating SARM1 and treating various diseases and conditions, e.g., those caused by axonal degeneration. La présente divulgation concerne des composés de formule (1), des compositions les comprenant, et leurs procédés d'utilisation, y compris des utilisations dans la modulation de SARM1 et le traitement de diverses maladies et affections, par exemple celles provoquées par une dégénérescence axonale.