COMPOSITIONS AND METHODS FOR TREATING DISEASES RESPONSIVE TO AKG-VITAMIN B COADMINISTRATION

Compositions and methods for treating diseases that are responsive to the coadministration of AKG and certain B vitamins are described herein. In addition, compositions and methods for treating host animals that may not respond to AKG monotherapy, including treating host animals having inadequate or...

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Bibliographische Detailangaben
Hauptverfasser:	PALMER III, Francis R, FINNEMORE, Robb D, WELDON, Thomas D
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Compositions and methods for treating diseases that are responsive to the coadministration of AKG and certain B vitamins are described herein. In addition, compositions and methods for treating host animals that may not respond to AKG monotherapy, including treating host animals having inadequate or dysfunctional expression of enzymes involved in vitamin B metabolism and homeostasis, such as methylenetetrahydrofolate reductase (MTHFR), are described herein. L'invention concerne des compositions et des procédés de traitement de maladies qui sont sensibles à la co-administration d'AKG et de certaines vitamines B. De plus, l'invention concerne des compositions et des procédés pour traiter des animaux hôtes qui peuvent ne pas répondre à une monothérapie d'AKG, comprenant le traitement d'animaux hôtes ayant une expression inadéquate ou dysfonctionnelle d'enzymes impliquées dans le métabolisme et l'homéostasie de la vitamine B, telles que la méthylène tétrahydrofolate réductase (MTHFR).