KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF
The disclosure relates to KRAS inhibitor compounds having the structure of Formula (I), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRAS-associated diseases, disorders and conditions. L'invention concerne des composés inhibiteurs d...
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creator | LU, Jiasheng GE, Jian WU, Gang DU, Xianchao ZONG, Bin HE, Xiaolin WANG, Linxin SHI, Mengchao JI, Xiang KONG, Xianqi ZHOU, Tianlun YE, Xiangsheng ZHANG, Qiguo CHEN, Dawei WU, Yanpeng |
description | The disclosure relates to KRAS inhibitor compounds having the structure of Formula (I), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRAS-associated diseases, disorders and conditions.
L'invention concerne des composés inhibiteurs de KRAS ayant la structure de formule (I), des compositions pharmaceutiques à base de ceux-ci, et des procédés d'utilisation correspondants pour inhiber, traiter et/ou prévenir des maladies, des troubles et des états pathologiques associés à KRAS. |
format | Patent |
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L'invention concerne des composés inhibiteurs de KRAS ayant la structure de formule (I), des compositions pharmaceutiques à base de ceux-ci, et des procédés d'utilisation correspondants pour inhiber, traiter et/ou prévenir des maladies, des troubles et des états pathologiques associés à KRAS.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND3DnIMVvD08_B08gzxDwpWcPRzUQjwcAzydXR2DQ3xdHb0UQgNdg1WCPFwDXL1d-NhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGRiaGhpZG5uaOhsbEqQIAow0m-w</recordid><startdate>20240613</startdate><enddate>20240613</enddate><creator>LU, Jiasheng</creator><creator>GE, Jian</creator><creator>WU, Gang</creator><creator>DU, Xianchao</creator><creator>ZONG, Bin</creator><creator>HE, Xiaolin</creator><creator>WANG, Linxin</creator><creator>SHI, Mengchao</creator><creator>JI, Xiang</creator><creator>KONG, Xianqi</creator><creator>ZHOU, Tianlun</creator><creator>YE, Xiangsheng</creator><creator>ZHANG, Qiguo</creator><creator>CHEN, Dawei</creator><creator>WU, Yanpeng</creator><scope>EVB</scope></search><sort><creationdate>20240613</creationdate><title>KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF</title><author>LU, Jiasheng ; GE, Jian ; WU, Gang ; DU, Xianchao ; ZONG, Bin ; HE, Xiaolin ; WANG, Linxin ; SHI, Mengchao ; JI, Xiang ; KONG, Xianqi ; ZHOU, Tianlun ; YE, Xiangsheng ; ZHANG, Qiguo ; CHEN, Dawei ; WU, Yanpeng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024119277A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LU, Jiasheng</creatorcontrib><creatorcontrib>GE, Jian</creatorcontrib><creatorcontrib>WU, Gang</creatorcontrib><creatorcontrib>DU, Xianchao</creatorcontrib><creatorcontrib>ZONG, Bin</creatorcontrib><creatorcontrib>HE, Xiaolin</creatorcontrib><creatorcontrib>WANG, Linxin</creatorcontrib><creatorcontrib>SHI, Mengchao</creatorcontrib><creatorcontrib>JI, Xiang</creatorcontrib><creatorcontrib>KONG, Xianqi</creatorcontrib><creatorcontrib>ZHOU, Tianlun</creatorcontrib><creatorcontrib>YE, Xiangsheng</creatorcontrib><creatorcontrib>ZHANG, Qiguo</creatorcontrib><creatorcontrib>CHEN, Dawei</creatorcontrib><creatorcontrib>WU, Yanpeng</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LU, Jiasheng</au><au>GE, Jian</au><au>WU, Gang</au><au>DU, Xianchao</au><au>ZONG, Bin</au><au>HE, Xiaolin</au><au>WANG, Linxin</au><au>SHI, Mengchao</au><au>JI, Xiang</au><au>KONG, Xianqi</au><au>ZHOU, Tianlun</au><au>YE, Xiangsheng</au><au>ZHANG, Qiguo</au><au>CHEN, Dawei</au><au>WU, Yanpeng</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF</title><date>2024-06-13</date><risdate>2024</risdate><abstract>The disclosure relates to KRAS inhibitor compounds having the structure of Formula (I), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRAS-associated diseases, disorders and conditions.
L'invention concerne des composés inhibiteurs de KRAS ayant la structure de formule (I), des compositions pharmaceutiques à base de ceux-ci, et des procédés d'utilisation correspondants pour inhiber, traiter et/ou prévenir des maladies, des troubles et des états pathologiques associés à KRAS.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF |
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