KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF

The disclosure relates to KRAS inhibitor compounds having the structure of Formula (I), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRAS-associated diseases, disorders and conditions. L'invention concerne des composés inhibiteurs d...

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Hauptverfasser: LU, Jiasheng, GE, Jian, WU, Gang, DU, Xianchao, ZONG, Bin, HE, Xiaolin, WANG, Linxin, SHI, Mengchao, JI, Xiang, KONG, Xianqi, ZHOU, Tianlun, YE, Xiangsheng, ZHANG, Qiguo, CHEN, Dawei, WU, Yanpeng
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creator LU, Jiasheng
GE, Jian
WU, Gang
DU, Xianchao
ZONG, Bin
HE, Xiaolin
WANG, Linxin
SHI, Mengchao
JI, Xiang
KONG, Xianqi
ZHOU, Tianlun
YE, Xiangsheng
ZHANG, Qiguo
CHEN, Dawei
WU, Yanpeng
description The disclosure relates to KRAS inhibitor compounds having the structure of Formula (I), pharmaceutical compositions thereof, and methods of use thereof for inhibiting, treating, and/or preventing KRAS-associated diseases, disorders and conditions. L'invention concerne des composés inhibiteurs de KRAS ayant la structure de formule (I), des compositions pharmaceutiques à base de ceux-ci, et des procédés d'utilisation correspondants pour inhiber, traiter et/ou prévenir des maladies, des troubles et des états pathologiques associés à KRAS.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title KRAS INHIBITORS AND PHARMACEUTICAL USES THEREOF
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