CDK INHIBITORS AND METHODS AND USE THEREOF

CDK INHIBITORS AND METHODS AND USE THEREOF

The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of CDK enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DIPIETRO, Lucian V, PITCH, Jessica, MCLEAN, Thomas H, FLEMING, Paul Robert, HE, Jing, TAYLOR, Alexander M, SCHOENHERR, Heike, RAYNOR, Kevin David, PABON, Nicolas A, BAUM, Erich W, ZHAO, Yuanchi
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of CDK enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with CDK signaling with the compounds and compositions of the disclosure. La présente invention concerne de nouveaux composés et des compositions pharmaceutiques de ceux-ci, ainsi que des méthodes d'inhibition de l'activité d'enzymes CDK faisant appel aux composés et compositions de l'invention. La présente invention concerne en outre, mais sans caractère limitatif, des méthodes de traitement de troubles associés à la signalisation de CDK faisant appel aux composés et compositions de l'invention.