NOVEL THIAZOLE DERIVATIVE

The present invention provides a thiazole derivative that has an ALK5 inhibitory action and that is represented by formula (1) (refer to the description with respect to R1, R2, and Z in the formula), or a pharmaceutically acceptable salt thereof. La présente invention concerne un dérivé de thiazole...

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Bibliographische Detailangaben
Hauptverfasser:	OHMOTO, Hiroshi, ARAI, Mai, HANADA, Mitsuharu, SAWA, Masaaki
Format:	Patent
Sprache:	eng ; fre ; jpn
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a thiazole derivative that has an ALK5 inhibitory action and that is represented by formula (1) (refer to the description with respect to R1, R2, and Z in the formula), or a pharmaceutically acceptable salt thereof. La présente invention concerne un dérivé de thiazole qui a une action inhibitrice d'ALK 5 et qui est représenté par la formule (1) (voir la description pour R1, R2, et Z dans la formule), ou un sel pharmaceutiquement acceptable de celui-ci. 本願発明により、下式（１）（式中、Ｒ１、Ｒ２およびＺは明細書参照）で示される、ＡＬＫ５阻害作用を有するチアゾール誘導体またはその薬学的に許容される塩が提供される。