METHOD FOR CONSTRUCTING ACUTE ANXIETY MODEL OF LABORATORY ANIMAL AND USE THEREOF

A method for constructing an acute anxiety model of a laboratory animal and a use thereof. By means of injecting exogenous parathyroid hormone-related protein in vivo into a laboratory animal, the laboratory animal generates anxiety symptoms within a short period of time, thereby obtaining an acute...

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Hauptverfasser: JUAN, Shi Rui, ZHANG, Zhi Gang, HONG, Yu Chuan, XIAO, Qian, LIU, Dan, TU, Jie, HU, Hao Hao, XUAN, Shou Min, ZHOU, Xin Yi, XU, Xi Rong
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:A method for constructing an acute anxiety model of a laboratory animal and a use thereof. By means of injecting exogenous parathyroid hormone-related protein in vivo into a laboratory animal, the laboratory animal generates anxiety symptoms within a short period of time, thereby obtaining an acute laboratory animal model having anxiety symptoms. The preset acute anxiety model of a laboratory animal has the advantages of quick effectiveness, a short modeling time, an obvious anxiety phenotype, etc., thereby addressing the problems of additional injuries being prone to occurring, inhibited ventilation for laboratory animals, differences in binding pressure, additional dizziness of the laboratory animals, etc. during a modeling process in conventional acute anxiety models of animals, and facilitating mechanism research as well as drug research and development for anxiety disorders. La présente invention concerne un procédé de construction d'un modèle d'anxiété aiguë d'un animal de laboratoire et son utilisation