PEPTIDE HAVING SKIN WHITENING ACTIVITY, AND USE THEREOF

The peptide of the present invention inhibits melanosome invagination in keratinocytes and promotes melanosome degradation, thereby having skin whitening activity. The peptide of the present invention can be used as an active ingredient of a drug for treating or preventing hyperpigmentation diseases...

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Hauptverfasser: LEE, Eung Ji, JUNG, Da Won, JEONG, Min Kyeong, CHUNG, Yong Ji, KIM, Eun Mi
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Sprache:eng ; fre ; kor
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JUNG, Da Won
JEONG, Min Kyeong
CHUNG, Yong Ji
KIM, Eun Mi
description The peptide of the present invention inhibits melanosome invagination in keratinocytes and promotes melanosome degradation, thereby having skin whitening activity. The peptide of the present invention can be used as an active ingredient of a drug for treating or preventing hyperpigmentation diseases caused by melanosome hyperpigmentation, or as an active ingredient of skin whitening cosmetics. La présente invention concerne un peptide qui inhibe l'invagination du mélanosome dans les kératinocytes et favorise la dégradation du mélanosome, ayant ainsi une activité de blanchiment de la peau. Le peptide selon la présente invention peut être utilisé en tant que principe actif d'un médicament pour le traitement ou la prévention de maladies d'hyperpigmentation provoquées par une hyperpigmentation de mélanosome, ou en tant que principe actif de produits cosmétiques de blanchiment de la peau. 본 발명의 펩타이드는 각질형성세포에서 멜라노좀의 함입을 억제하고, 멜라노좀의 분해를 촉진함으로써, 피부 미백활성을 갖는다. 본 발명의 펩타이드는 과도한 멜라노좀의 침착으로 인해 발생한 과다색소침착 질환의 치료 또는 예방용 약물의 활성성분 또는 피부미백용 화장료의 유효성분으로 사용될 수 있다.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
title PEPTIDE HAVING SKIN WHITENING ACTIVITY, AND USE THEREOF
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